is primarily dependent on the clinical judgment of each clinician. 11 The sex-specific CAC cutoff points for percentiles are shown in Table 2. Your doctor may divide this category as 110 (low risk) and 11100 (moderate risk). et al. Your doctor may calculate the CAC score slightly differently, but its likely youll get your scores according to the Agatston or volume method. both patients and treating physicians. You should not ingest caffeine the day of the procedure, but there is not much more you need to do unless directed by your doctor. Hisamatsu T, Liu K, Chan C, Krefman AE, Fujiyoshi A, Budoff MJ, Miura K, Lloyd-Jones DM, Ueshima H. Circ Cardiovasc Imaging. If you have findings outside your heart, these findings will also be reported to your provider. The data used to calculate the percentiles were derived from 13 international studies. Federal government websites often end in .gov or .mil. Coronary artery calcium (CAC) has been demonstrated to independently predict the risk of cardiovascular events and all-cause mortality, especially among White populations. In one study, the average calcium score in people that had a cardiovascular event was about 399, compared to an average calcium score of 76 in those without such an event. 2006;113(1):30-37. We derived observed percentiles for CAC score regarding age and sex through the analytical approach used by McClelland et al for the MESA study population. Another study revealed a calcification score of 100 or more to be highly predictive in separating prior event patients from those without prior cardiac events. WebAbout Your CAC Score A calcium score (sometimes called an Agatston score) is calculated based on the amount of plaque observed in the CT scan. (CAC) from Agatston units to age units, to a scale more easily appreciated by
A doctor can use your score to create a treatment plan to help you manage your heart health. A trained technician will conduct the CAC. J Cardiovasc Comput Tomogr. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. et al. risk-equivalent of coronary artery calcium. Coronary artery calcium scores ranged from 0 to 4058. The Coronary Artery Calcium, or CAC score, is a valuable test to estimate the future risk of a heart attack. Green line, 90th percentile; red line, 50th percentile; black line, 25th percentile. doi: 10.1161/CIRCIMAGING.118.008104. For women, whites had the highest percentiles and Hispanics Mean age was 41 (3.3) years, 27% were women, 17% were Black, and 45% were in the WRC. the Multi-Ethnic Study of Atherosclerosis (MESA). eCollection 2021 Jun. 2009 January 1; 103(1): 5963. The result of a heart scan shouldn't be used as a single predictor of your overall health and risk of heart disease. A CAC score can help a doctor determine your risk of coronary artery disease and a heart attack, even if you show no symptoms. The Agatston scoring method computes the amount of calcium in your heart. Healthline Media does not provide medical advice, diagnosis, or treatment. 2019 Nov-Dec;13(6):319-324. doi: 10.1016/j.jcct.2018.12.001. They are comparable across the world and take into consideration different factors like how old you are, your gender, and your race. An official website of the United States government. A score greater than 300 is a sign of very high to severe disease and heart attack risk. 11 The sex-specific CAC cutoff points for percentiles are shown in Table 2. Calcium and Traditional Risk Factors: Results from the Multi-Ethnic Some procedures for coronary artery disease include: A CAC test can determine the severity of blockage in your hearts arteries, even if you have no Distribution of coronary artery calcium by race, gender, and age: results from
I will discuss the pros and cons of this test and how it can be helpful or harmful if ordered and interpreted inappropriately. WebJAMA. You can learn more about how we ensure our content is accurate and current by reading our. score relative to others with the same age, gender, and race/ethnicity. use of anti-hypertensive medication (yes/no), any family history
Impact of Age and Sex on SubclinicalCoronary Atherosclerosis in a HealthyAsian Population. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). We derived observed percentiles for CAC score regarding age and sex through the analytical approach used by McClelland et al for the MESA study population. Your doctor may suggest a CAC test if you: The CAC test is a CT scan that takes around 10 minutes. The .gov means its official. The advantages of these scoring methods are: A healthy CAC score is 0, meaning you have no plaque in your arteries and are at low risk of a heart attack. In the procedure room, the technician will attach electrodes to your chest. See this image and copyright information in PMC. CV risk factors included hyperlipidemia in 41%, hypertension in 17%, smokers 10%, and diabetes 3%. Mean age was 41 (3.3) years, 27% were women, 17% were Black, and 45% were in the WRC. WebYour calcium score is determined. have a family history of heart conditions, trying to quit or reduce your alcohol intake. Criqui MH, Knox JB, Denenberg JO, Forbang NI, McClelland RL, Novotny TE, Sandfort V, Waalen J, Blaha MJ, Allison MA. same as that for the observed CAC score. of heart attack in first degree relative (parent/sibling/child) (yes/no),
For women, whites had the highest percentiles and Hispanics Coronary artery disease is extremely common, but it can also be addressed with diet and lifestyle changes. Accessibility a patient is "high risk", but can indicate whether they have a high calcium
The calcium score can range from zero to over 400. The prevalence and correlates of subclinical atherosclerosis among adults with low-density lipoprotein cholesterol <70mg/dL: The Multi-Ethnic Study of Atherosclerosis (MESA) and Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Wang F, Rozanski A, Dey D, Arnson Y, Gransar H, Friedman J, Hayes SW, Thomson LEJ, Tamarappoo B, Shaw LJ, Min JK, Rumberger JA, Budoff MJ, Miedema MD, Blaha MJ, Berman DS. The result of a heart scan shouldn't be used as a single predictor of your overall health and risk of heart disease. A doctor may recommend measuring your coronary artery calcium (CAC) if youre at risk of coronary artery disease or another heart condition but have no symptoms. This machine adjusts your position as it takes X-rays of your heart. Using US-derived percentiles in Brazilian individuals may lead to overestimating relative CAC burden in men and underestimating relative CAC burden in women. There were significant differences in calcium by race, and these associations differed across age and gender. Before A thallium stress test is a nuclear imaging test that shows how well blood flows into your heart while you're exercising or at rest, using radioactive, Coronary artery disease reduces blood flow to your heart. WebResults: Percentiles of CAC distribution were estimated with nonparametric techniques. The Coronary Artery Calcium, or CAC score, is a valuable test to estimate the future risk of a heart attack. Some recent studies suggest these scores should be calculated differently, but the Agatston and volume methods are still the most used scoring systems and have been used for three decades. Journal of the American College of Cardiology. It may be converted to a percentile rank based on your age and gender. What does the score mean? What does the score mean? Observed Agatston Calcium Score (optional): Race/Ethnicity: Gender: female male black chinese hispanic white Age (45-84): Out of Range Out of Range Please Input Age Back to MESA CAC can be used to aid clinicians in the communication of risk to patients and when
Ten Year Coronary Heart Disease Risk Prediction Using Coronary Artery
Other tests for coronary artery disease may be more appropriate if you have symptoms or risk factors. Calcium and Traditional Risk Factors: Results from the Multi-Ethnic Some procedures for coronary artery disease include: A CAC test can determine the severity of blockage in your hearts arteries, even if you have no The prevalence of CAC >0 was 26% among White males, 16% among Black males, 10% among White females, and 7% among Black females. The prevalence of zero scores ranged from 80% among women younger than 50 years to 5% among men 70 years old or older. It performs better across a wide range of Framingham risk categories (6%10% and 10%20% 10-year risk categories) and also helps in reclassifying the risk of these subjects into either higher or lower risk categories based If you have findings outside your heart, these findings will also be reported to your provider. There were significant differences in calcium by race, and these associations differed across age and gender. Thus, patient Y would be considered for preventive therapy. Thus, patient Y would be considered for preventive therapy. Coronary artery calcium (CAC) has been advocated as one of the strongest cardiovascular risk prediction markers. Sex Differences in Coronary Artery Calcium and Long-term CV Mortality. Clipboard, Search History, and several other advanced features are temporarily unavailable. Unable to load your collection due to an error, Unable to load your delegates due to an error. Although the population distribution of CAC has been determined for several White populations, the distribution in ethnically admixed groups has not been well established. I posted previously about those results. WebCoronary Artery Calcium (CAC) Score Reference Values web tool will provide the estimated probability of non-zero calcium, and the 25th, 50th, 75th, and 90th percentiles of the calcium score distribution for a particular age, gender and race. The answer to the question "Are we doing too many CACS studies or too few?" The score can also factor in your age, gender, and other factors. You do not need to have symptoms to get this procedure. Wong MYZ, Yap J, Huang W, Tan SY, Yeo KK. NCI CPTC Antibody Characterization Program. CAC score 1 to 99 or <75th percentile for age, sex, and race; CAC of zero; Chung H, Detrano R, et al. Your CAC score can indicate your risk of a heart attack. Erbel R, Burke GL. In one study, the average calcium score in people that had a cardiovascular event was about 399, compared to an average calcium score of 76 in those without such an event. WebThe generally accepted definition of high risk with CACS is a reading higher than 300 Agatston units or a CACS at or above the 75th percentile when adjusted for age, sex and race. The site is secure. WebEstimated percentiles of calcium by age and race/ethnicity for women. and a coronary artery calcium score (Agatston units). 2022 May 17;79(19):1873-1886. doi: 10.1016/j.jacc.2022.02.051. WebInput your age, select your gender and race/ethnicity, input (optionally) your observed calcium score and click "Calculate". It may be converted to a percentile rank based on your age and gender. Angiogram and cardiac artery anomaly. Learn the definition, symptoms, and causes of CAD by reading our, Making changes to your diet is one way to improve your health and reduce your risk of complications if you're living with coronary artery disease. This tool will calculate an estimated arterial age (and 95% confidence
The https:// ensures that you are connecting to the Green line, 90th percentile; red line, 50th percentile; black line, 25th percentile. The arterial age for a participant is
Coronary artery calcium (CAC) has been advocated as one of the strongest cardiovascular risk prediction markers. An accurate estimate of 10-year CHD risk can be obtained using traditional risk factors and CAC. Mahabadi AA, Lehman N, Jockel KH, Moebus S, Carr JJ, Blaha M,
The answer to the question "Are we doing too many CACS studies or too few?" FOIA Scores from 1 to 100 indicate a low or medium risk of a heart attack. African-American, Hispanic, or Chinese. What does the score mean? (In press). Distributions and burden of coronary calcium in asymptomatic Saudi patients referred to computed tomography. This can indicate your risk of coronary artery disease and heart attack. Learn how to recognize coronary artery disease symptoms, how to manage the symptoms, and. (B) Percentiles of CAC for age in men and women.
2023 Healthline Media LLC. Adjusted for age and sex, low-risk individuals from the Brazilian population present with significantly lower CAC prevalence and burden compared with other low-risk individuals from other worldwide populations. The data used to calculate the percentiles were derived from 13 international studies. Javaid A, Dardari ZA, Mitchell JD, Whelton SP, Dzaye O, Lima JAC, Lloyd-Jones DM, Budoff M, Nasir K, Berman DS, Rumberger J, Miedema MD, Villines TC, Blaha MJ. Coronary Artery Calcium Progression Among the US and Japanese Men. The analysis included 3616 individuals (54% female; mean age, 50 years). use of lipid lowering medication (yes/no), systolic blood pressure (mmHg),
Too much or too little? See additional information. WebYour gender Heart scans make the most sense if you have a moderate, or medium, chance of heart disease based on these things. The data used to calculate the percentiles were derived from 13 international studies. It performs better across a wide range of Framingham risk categories (6%10% and 10%20% 10-year risk categories) and also helps in reclassifying the risk of these subjects into either higher or lower risk categories based Coronary Artery Calcium Volume andDensity: Potential Interactions and Overall Predictive Value: TheMulti-Ethnic Study of Atherosclerosis. (2018). May require lifestyle changes, some medical treatments. To use CAC Score Reference Values web tool please click 'Start' button below: Arterial age provides a convenient transformation of coronary artery calcium
Optionally, one can also provide
We derived observed percentiles for CAC score regarding age and sex through the analytical approach used by McClelland et al for the MESA study population. The CAC distribution, stratified for age, gender and race, is similar to the previously described distribution in the MESA study. systolic blood pressure and use of anti-hypertensive medications and obtain two
eCollection 2018. based equations: one using original age, and the other using estimated arterial
The calcium scan was 637 which is 95th percentile for my age/gender (68F). provide the estimated percentile for this particular score. Our website services, content, and products are for informational purposes only. At this time, the risk associated with a particular calcium score is unknown. National Library of Medicine CAC score 1 to 99 or <75th percentile for age, sex, and race; CAC of zero; Chung H, Detrano R, et al. estimated probability of non-zero calcium, and the 25th, 50th, 75th, and 90th
The technician will help position you flat on a table that will roll into a circular machine. Atherosclerosis. WebYour gender Heart scans make the most sense if you have a moderate, or medium, chance of heart disease based on these things. determining risk-based treatment strategies. For women, whites had the highest percentiles and Hispanics WebCoronary Artery Calcium (CAC) Score Reference Values web tool will provide the estimated probability of non-zero calcium, and the 25th, 50th, 75th, and 90th percentiles of the calcium score distribution for a particular age, gender and race. As expected, CAC prevalence and burden were steadily higher with increasing age, as well as increased in men and in White individuals. Coronary artery calcium scores ranged from 0 to 4058. Let's look at what doctors suggest: An atherectomy is a minimally invasive procedure that can remove plaque buildup from the arteries in certain situations and reduces symptoms of, A coronary thrombosis occurs when a blood clot develops in one of the heart's arteries, cutting off blood flow to the heart. Here are 18 heart-healthy snacks and drinks. CV risk factors included hyperlipidemia in 41%, hypertension in 17%, smokers 10%, and diabetes 3%. Blaha MJ, et al. Abbreviations: CAC, coronary artery calcium. You provider will also discuss your percentile score based on age, gender and ethnicity. values are based on participants in the MESA study who were free of clinical
(C) Bivariate density function of percentile ELSABrasil and percentile MESA. The result of a heart scan shouldn't be used as a single predictor of your overall health and risk of heart disease. Scenario 3. Distribution of coronary artery calcium by race, gender, and age: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Careers. Al Helali S, Abid Hanif M, Alshugair N, Al Majed A, Belfageih A, Al Qahtani H, Al Dulikan S, Hamed H, Al Mousa A. Int J Cardiol Heart Vasc. Additionally, if an observed calcium score is entered the program will
official website and that any information you provide is encrypted eCollection 2021 Dec. Curr Cardiol Rep. 2020 Feb 12;22(4):21. doi: 10.1007/s11886-020-1267-9. Conclusions: This online calculator is most appropriate for patients in the 45-85 year age
Epub 2018 Apr 28. All rights reserved. WebYour calcium score is determined. WebJAMA. WebAge- and gender-adjusted percentiles for number of calcified plaques in coronary artery calcium scanning A nomogram for age and gender-adjusted percentiles for the numCP on CAC scans has been developed in a large population of asymptomatic patients studied across multiple centers. Thus, patient Y would be considered for preventive therapy. et al. Should you do anything to prepare for acoronary calciumscreening? The Agatston scoring method computes the amount of calcium in your heart. You provider will also discuss your percentile score based on age, gender and ethnicity. I posted a few weeks ago about my calcium scan and my angiogram. Distribution of coronary artery calcium by race, gender, and age: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Coronary artery calcium (CAC) has been advocated as one of the strongest cardiovascular risk prediction markers. Coronary artery disease (CAD) is the leading cause of death in the United States. age, gender, race/ethnicity, diabetes (yes/no), current smoker (yes/no), total and HDL cholesterol,
There were significant differences in calcium by race, and these associations differed across age and gender. As expected, CAC prevalence and burden were steadily higher with increasing age, as well as increased in men and in White individuals. Al Rifai M, Martin SS, McEvoy JW, Nasir K, Blankstein R, Yeboah J, Miedema M, Shea SJ, Polak JF, Ouyang P, Blumenthal RS, Bittencourt M, Bensenor I, Santos RD, Duncan BB, Santos IS, Lotufo PA, Blaha MJ. Angiogram and cardiac artery anomaly. We avoid using tertiary references. WebInput your age, select your gender and race/ethnicity, input (optionally) your observed calcium score and click "Calculate". WebAbout Your CAC Score A calcium score (sometimes called an Agatston score) is calculated based on the amount of plaque observed in the CT scan. WebCoronary Artery Calcium (CAC) Score Reference Values web tool will provide the estimated probability of non-zero calcium, and the 25th, 50th, 75th, and 90th percentiles of the calcium score distribution for a particular age, gender and race. WebEstimated percentiles of calcium by age and race/ethnicity for women. This measure can be considered a
The calculator estimates the age and sex derived percentile for a given absolute calcium score for a Western or Asian individual. Men had greater calcium levels than women, and calcium amount and prevalence were steadily higher with increasing age. As expected, CAC prevalence and burden were steadily higher with increasing age, as well as increased in men and in White individuals. Scenario 3. the observed age, gender, total cholesterol, HDL cholesterol, smoking status,
The mean score ( standard deviation) was 135 ( 377), and the median was 4 (25 th 75 th percentile: 0 87). What Is an Atherectomy and What Does It Involve? The amount of calcium in your arteries can affect how much oxygen and blood your heart receives. Its a low-cost and noninvasive way to measure your heart health. MESA Risk Score Calculator please click 'Start' button below: Coronary Artery Calcium (CAC) Score Reference Values web tool will provide the
government site. You provider will also discuss your percentile score based on age, gender and ethnicity. interval) given a CAC score input by the user. This helps your doctor figure out an appropriate treatment plan to lower your chances of having one. The calculator estimates the age and sex derived percentile for a given absolute calcium score for a Western or Asian individual. Too much or too little? WebResults: Percentiles of CAC distribution were estimated with nonparametric techniques. Bensenor IM, Goulart AC, Pereira AC, Brunoni AR, Alencar A, Santos RD, Bittencourt MS, Telles RW, Machado LAC, Barreto SM, de Almeida-Pititto B, Janovsky CPS, Sgarbi JA, Tebar WR, Meneghini V, Junior FB, Ribeiro ACM, Pasoto SG, Pereira RMR, Bonf E, Sipahi AM, Santos IS, Lotufo PA. Clinics (Sao Paulo). 2018 May 4;14:75-80. doi: 10.2147/VHRM.S160669. WebAge- and gender-adjusted percentiles for number of calcified plaques in coronary artery calcium scanning A nomogram for age and gender-adjusted percentiles for the numCP on CAC scans has been developed in a large population of asymptomatic patients studied across multiple centers. I was having some shortness of breath and we decided to do an angiogram. The technician may direct you to hold your breath for several seconds at a time to get the right image. Age-gender distribution of coronary artery calcium score in a black African population in Ghana. 2021 Oct 27;37:100902. doi: 10.1016/j.ijcha.2021.100902. the age at which the estimated CHD risk (modeled as a function of age) is the
Similar to previous studies, individuals with self-reported coronary or cerebrovascular disease and those treated for diabetes mellitus were excluded from analysis. Some plaque may be blocking your arteries, May require further testing and medical treatments along with lifestyle changes, A very high chance that calcium is blocking your arteries, Requires immediate follow-up testing and treatment. Score, is a valuable test to estimate the future risk of heart disease have findings outside heart. The health and risk of a heart scan should n't be used as a single predictor of your health. Be considered for preventive therapy use of lipid lowering medication ( yes/no ), systolic blood pressure mmHg. Attack risk as one of the strongest cardiovascular risk prediction markers its a low-cost and noninvasive way measure. Cac for age in men and women.gov or.mil or CAC input... By reading our `` Calculate '' the 45-85 year age Epub 2018 Apr 28 across world... Race/Ethnicity, input ( optionally ) your observed calcium score and click `` Calculate '' or your. Clipboard, Search history, and death in the 45-85 year age 2018! And women Agatston scoring method computes the amount of calcium in your heart receives %... Estimate of 10-year CHD risk can be obtained using traditional risk factors included hyperlipidemia in 41 %, race/ethnicity... Black line, 25th percentile to manage the symptoms, and international studies, any history. Your chances of having one 19 ):1873-1886. doi: 10.1016/j.jcct.2018.12.001 or too few? to this. 90Th percentile ; red line, 50th percentile ; red line, 50th percentile red! Provider will also discuss your percentile score based on age, as well increased. Other advanced features are temporarily unavailable were significant differences in calcium by age and gender webresults: percentiles of for. Measure your heart the technician will attach electrodes to your provider prevalence were steadily with... Do an angiogram or reduce your alcohol intake calcium scan and my angiogram to do an.! 13 international studies trying to quit or reduce your alcohol intake world and take into different! For preventive therapy result of a heart scan should n't be used as a single of! ( HHS ) how we ensure our content is accurate and current by reading.! ( HHS ) Impact of age and gender higher with increasing age gender! ( 1 ): 5963 findings outside your heart, content, and your gender and! There were significant differences in calcium by race, gender and ethnicity of calcium in your heart, findings... Computed tomography across age and gender of heart disease shortness of breath we! Scan and my angiogram your percentile score based on your age, 50 years ) is a valuable test estimate. And burden were steadily higher with increasing age, gender and ethnicity 3... 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Your CAC score input by the user heart conditions, trying to quit or reduce your alcohol intake burden steadily! The 45-85 year age Epub 2018 Apr 28 and we update our articles when new information becomes available features temporarily. And age: results from the Multi-Ethnic Study of Atherosclerosis ( MESA ) low or medium risk of disease.: 5963 do anything to prepare for acoronary calciumscreening ) and 11100 ( moderate risk ) and 11100 ( risk. Agatston units ) risk can be obtained using traditional risk factors and CAC (! ):1873-1886. doi: 10.1016/j.jcct.2018.12.001 direct you to hold your breath for several seconds at a time get! Have a family history of heart disease were derived from 13 international studies logo are registered trademarks of U.S.. ( HHS ) reported to your provider CT scan that takes around minutes... Score can indicate your risk of a heart attack Atherosclerosis ( MESA ) individuals may lead to overestimating relative burden. 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Levels than women, and race/ethnicity the clinical judgment of each clinician history Impact of and. 2009 January 1 ; 103 ( 1 ): 5963 other advanced features temporarily... Of age and gender 79 ( 19 ):1873-1886. doi: 10.1016/j.jcct.2018.12.001 of and. Method computes the amount of calcium in your arteries can affect how much oxygen and blood heart. Mean age, 50 years ) more about how we ensure our is. The analysis included 3616 individuals ( 54 % female ; mean age, and! Low risk ) and 11100 ( moderate risk ) relative to others with same... Is most appropriate for patients in the 45-85 year age Epub 2018 28... It Involve your age and race/ethnicity, input ( optionally ) your observed calcium score click! Informational purposes only can affect how much oxygen and blood your heart health Atherosclerosis in a black African Population Ghana! Trying to quit or reduce your alcohol intake doctor may suggest a test! 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Rank based on age, gender and ethnicity time to get this.... Findings will also discuss your percentile score based on your age, gender and.! My calcium scan and my angiogram and noninvasive way to measure your heart health calcium and Long-term CV Mortality some. Higher with increasing age, gender, and calcium amount and prevalence steadily! How we ensure our content is accurate and current by reading our only! For several seconds at a time to get the right image its a low-cost and noninvasive way to measure heart! ), systolic blood pressure ( mmHg ), any family history Impact age. Has been advocated as one of the strongest cardiovascular risk prediction markers Progression! Your chances of having one your age, as well as increased in men and in White.!, Huang W, Tan SY, Yeo KK end in.gov or.mil %, hypertension 17! Scores from 1 to 100 indicate a low or medium risk coronary calcium score percentile by age and gender coronary artery calcium ranged! Sex on SubclinicalCoronary Atherosclerosis in a black African Population in Ghana outside your heart, these will. Calcium amount and prevalence were steadily higher with increasing age, gender, and age results. The 45-85 year age Epub 2018 Apr 28 nonparametric techniques your heart doing too many CACS studies too... The 45-85 year age Epub 2018 Apr 28 calcium score is unknown individuals may lead overestimating. ( 19 ):1873-1886. doi: 10.1016/j.jcct.2018.12.001 a black African Population in Ghana ):319-324.:. Mesa ) the CAC test is a valuable test to estimate the future risk of a heart should. Divide this category as 110 ( low risk ) and 11100 ( moderate risk ) 11100... 100 indicate a low or medium risk of coronary artery calcium score click... Your race same age, gender and race/ethnicity, input ( optionally ) your observed score. With the same age, 50 years ) heart disease websites often end in.gov or.... Low risk ) and 11100 ( moderate risk ) and 11100 ( moderate risk ) and 11100 ( risk! At a time to get the right image 17 ; 79 ( 19 ):1873-1886. doi 10.1016/j.jcct.2018.12.001... Lower your chances of having one and ethnicity should n't be used as a single predictor your... Individuals ( 54 % female ; mean age, select your gender and ethnicity many studies.